Cover: A Review of Barriers to Medication Adherence

A Review of Barriers to Medication Adherence

A Framework for Driving Policy Options

Published Oct 2, 2009

by Walid F. Gellad, Jerry Grenard, Elizabeth A. McGlynn

Download eBook for Free

Full Document

FormatFile SizeNotes
PDF file 0.5 MB

Use Adobe Acrobat Reader version 10 or higher for the best experience.

Summary Only

FormatFile SizeNotes
PDF file 0.1 MB

Use Adobe Acrobat Reader version 10 or higher for the best experience.

Failure to adhere to recommended medication regimens is a real problem that has negative consequences for patients, providers, health plans, employers, industry, and society. The national dialogue on health reform that is currently under way includes a discussion of ways to improve care for persons with chronic disease and to improve the value and efficiency of health care. Strategies to improve adherence to medication therapy fall squarely in these discussions, since nonadherence affects the ability to effectively manage and control chronic diseases and contributes to the costs society incurs. This literature review was requested as background for a conference focusing on policy options to improve medication adherence. It identifies barriers to medication adherence with a strong evidence base and discusses key lessons from the literature that are relevant for the policy discussion.

The research in this report was sponsored by Mehlman Vogel Castagnetti, Inc. and conducted by RAND Health.

This report is part of the RAND technical report series. RAND technical reports may include research findings on a specific topic that is limited in scope or intended for a narrow audience; present discussions of the methodology employed in research; provide literature reviews, survey instruments, modeling exercises, guidelines for practitioners and research professionals, and supporting documentation; or deliver preliminary findings. All RAND reports undergo rigorous peer review to ensure that they meet high standards for research quality and objectivity.

This document and trademark(s) contained herein are protected by law. This representation of RAND intellectual property is provided for noncommercial use only. Unauthorized posting of this publication online is prohibited; linking directly to this product page is encouraged. Permission is required from RAND to reproduce, or reuse in another form, any of its research documents for commercial purposes. For information on reprint and reuse permissions, please visit

RAND is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.