Clinical guidelines for colorectal cancer (CRC) screening suggest use of either stool-based tests or colonoscopy. We conducted a cost-effectiveness analysis to compare 2 mailed outreach strategies to increase CRC screening.
This paper examines the validity of the CRC-SPIN model and colonoscopy sensitivity assumptions. We find that colonoscopy may be less accurate than currently assumed, especially for diminutive adenomas.
Higher rates of colorectal cancer incidence among black patients are primarily driven by lower rates of colorectal cancer screening. Our findings highlight the need to increase black patients' access to quality screening to reduce colorectal cancer incidence and mortality.
Screenings for breast cancer and colon cancer dropped dramatically during the early months of the coronavirus pandemic, but use of the procedures returned to near-normal levels by the end of July 2020.
This study aimed to describe strategies CHCs use to integrate care with specialists and examine whether more strongly integrated CHCs have higher rates of screening for colorectal and cervical cancers and report better communication with specialists.
Even relatively small delays in diagnostic testing after an abnormal cancer screening test can reduce screening effectiveness, though the impact varies by cancer type.
Exposures derived from EHRs may be misclassified, leading to biased estimates of their association with outcomes of interest: finite mixture models can correct biases with no loss of efficiency.
Patients prefer less invasive approaches such as fecal immunochemical test (FIT) for colorectal cancer screening, but the effectiveness of FIT depends on annual screenings for those with negative test results and colonoscopy if FIT tests are positive.
More research is needed to determine whether the observed variation in genomic testing for lung and colorectal cancer reflects appropriate or inappropriate care.
Each of the diagnostics for colorectal cancer has a different level of evidence supporting its ability to detect cancer and associated risks of serious adverse effects. More research is needed to clarify the evidence base.
This study systematically reviewed the evidence on the effectiveness, diagnostic accuracy, and harms of colonoscopy, flexible sigmoidoscopy, computed tomographic colonography, and stool tests for colorectal cancer screening.
Patients who visited their primary care provider one or more times were almost twice as likely to be screened for colorectal cancer and about 30 percent more likely receive a follow-up colonoscopy after a positive screening result.
Comparative modeling of colorectal cancer screening methods for previously unscreened adults found that the use of four strategies over different intervals between the ages of 50 and 75 years yielded a comparable balance of benefit and burden.
There is no evidence that state-mandated private health insurance coverage affected the rate of colorectal cancer screening for men or women aged 51-64, compared with Medicare-eligible adults.