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Colorectal Cancer

Journal Article
Cost Effectiveness of Mailed Outreach Programs for Colorectal Cancer Screening: Analysis of a Pragmatic, Randomized Trial
Clinical guidelines for colorectal cancer (CRC) screening suggest use of either stool-based tests or colonoscopy. We conducted a cost-effectiveness analysis to compare 2 mailed outreach strategies to increase CRC screening.
Sep 15, 2022
Journal Article
Too Good to Be True? Evaluation of Colonoscopy Sensitivity Assumptions Used in Policy Models
This paper examines the validity of the CRC-SPIN model and colonoscopy sensitivity assumptions. We find that colonoscopy may be less accurate than currently assumed, especially for diminutive adenomas.
Aug 17, 2022
Journal Article
Cost-Effectiveness of Community-to-Clinic Tailored Navigation for Colorectal Cancer Screening in an Underserved Population: Economic Evaluation Alongside a Group-Randomized Trial
Adding community-to-clinic tailored navigation to a community-based colorectal cancer screening promotion program may be highly cost-effective.
May 13, 2022
Journal Article
Black and White Differences in Colorectal Cancer Screening and Screening Outcomes: A Narrative Review
Higher rates of colorectal cancer incidence among black patients are primarily driven by lower rates of colorectal cancer screening. Our findings highlight the need to increase black patients' access to quality screening to reduce colorectal cancer incidence and mortality.
May 27, 2021
News Release
Use of Common Cancer Screenings Rebounded Quickly After Dropping at Start of the Pandemic
Screenings for breast cancer and colon cancer dropped dramatically during the early months of the coronavirus pandemic, but use of the procedures returned to near-normal levels by the end of July 2020.
Mar 22, 2021
Journal Article
Association of Primary and Specialty Care Integration on Physician Communication and Cancer Screening in Safety-Net Clinics
This study aimed to describe strategies CHCs use to integrate care with specialists and examine whether more strongly integrated CHCs have higher rates of screening for colorectal and cervical cancers and report better communication with specialists.
Feb 12, 2021
Journal Article
Effect of Time to Diagnostic Testing for Breast, Cervical, and Colorectal Cancer Screening Abnormalities on Screening Efficacy: A Modeling Study
Even relatively small delays in diagnostic testing after an abnormal cancer screening test can reduce screening effectiveness, though the impact varies by cancer type.
Jan 24, 2018
Journal Article
Accounting for Misclassification in Electronic Health Records-derived Exposures Using Generalized Linear Finite Mixture Models
Exposures derived from EHRs may be misclassified, leading to biased estimates of their association with outcomes of interest: finite mixture models can correct biases with no loss of efficiency.
Dec 7, 2017
Journal Article
Follow-up of Positive Fecal Test Results: Sooner Is Better, but How Much Better?
Patients prefer less invasive approaches such as fecal immunochemical test (FIT) for colorectal cancer screening, but the effectiveness of FIT depends on annual screenings for those with negative test results and colonoscopy if FIT tests are positive.
May 23, 2017
Journal Article
Medical Oncologists' Experiences in Using Genomic Testing for Lung and Colorectal Cancer Care
More research is needed to determine whether the observed variation in genomic testing for lung and colorectal cancer reflects appropriate or inappropriate care.
Mar 13, 2017
Journal Article
Misclassification Risk of Tier-Based Physician Quality Performance Systems
Current methods for determining whether a provider performs above or below a certain threshold do not always produce accurate results.
Nov 8, 2016
Journal Article
Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
Each of the diagnostics for colorectal cancer has a different level of evidence supporting its ability to detect cancer and associated risks of serious adverse effects. More research is needed to clarify the evidence base.
Oct 12, 2016
Journal Article
Influence of Age and Comorbidity on Colorectal Cancer Screening in the Elderly
Screening for colorectal cancer would benefit from re-evaluation of age-based guidelines as well as improved screening completion among the elderly.
Sep 13, 2016
Journal Article
Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
This study systematically reviewed the evidence on the effectiveness, diagnostic accuracy, and harms of colonoscopy, flexible sigmoidoscopy, computed tomographic colonography, and stool tests for colorectal cancer screening.
Jun 27, 2016
Journal Article
Association Between Primary Care Visits and Colorectal Cancer Screening Outcomes in the Era of Population Health Outreach
Patients who visited their primary care provider one or more times were almost twice as likely to be screened for colorectal cancer and about 30 percent more likely receive a follow-up colonoscopy after a positive screening result.
Jun 24, 2016
Journal Article
Estimation of Benefits, Burden, and Harms of Colorectal Cancer Screening Strategies: Modeling Study for the US Preventive Services Task Force
Comparative modeling of colorectal cancer screening methods for previously unscreened adults found that the use of four strategies over different intervals between the ages of 50 and 75 years yielded a comparable balance of benefit and burden.
Jun 21, 2016
Journal Article
Colorectal Cancer Screening and State Health Insurance Mandates
There is no evidence that state-mandated private health insurance coverage affected the rate of colorectal cancer screening for men or women aged 51-64, compared with Medicare-eligible adults.
Apr 25, 2016
Journal Article
Risks Associated with Anesthesia Services During Colonoscopy
Risk of complications within 30 days of a colonoscopy increases with the use of anesthesia services.
Apr 22, 2016
Journal Article
Time to Colonoscopy After Positive Fecal Blood Test in Four U.S. Health Care Systems
To reduce colorectal cancer mortality, positive fecal blood tests must be followed by colonoscopy.
Feb 22, 2016
Journal Article
Validation of Models Used to Inform Colorectal Cancer Screening Guidelines: Accuracy and Implications
We validated 3 colorectal cancer (CRC) microsimulation models against outcomes from the United Kingdom Flexible Sigmoidoscopy Screening (UKFSS) Trial, a randomized controlled trial that examined the effectiveness of one-time flexible sigmoidoscopy screening to reduce CRC mortality.
Jan 26, 2016

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RAND Topic:
Colorectal Cancer