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Colorectal Cancer

Journal Article

Effect of Time to Diagnostic Testing for Breast, Cervical, and Colorectal Cancer Screening Abnormalities on Screening Efficacy: A Modeling Study

Even relatively small delays in diagnostic testing after an abnormal cancer screening test can reduce screening effectiveness, though the impact varies by cancer type.

Jan 24, 2018
Journal Article

Accounting for Misclassification in Electronic Health Records-derived Exposures Using Generalized Linear Finite Mixture Models

Exposures derived from EHRs may be misclassified, leading to biased estimates of their association with outcomes of interest: finite mixture models can correct biases with no loss of efficiency.

Dec 7, 2017
Journal Article

Follow-up of Positive Fecal Test Results: Sooner Is Better, but How Much Better?

Patients prefer less invasive approaches such as fecal immunochemical test (FIT) for colorectal cancer screening, but the effectiveness of FIT depends on annual screenings for those with negative test results and colonoscopy if FIT tests are positive.

May 23, 2017
Journal Article

Medical Oncologists' Experiences in Using Genomic Testing for Lung and Colorectal Cancer Care

More research is needed to determine whether the observed variation in genomic testing for lung and colorectal cancer reflects appropriate or inappropriate care.

Mar 13, 2017
Journal Article

Misclassification Risk of Tier-Based Physician Quality Performance Systems

Current methods for determining whether a provider performs above or below a certain threshold do not always produce accurate results.

Nov 8, 2016
Journal Article

Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Each of the diagnostics for colorectal cancer has a different level of evidence supporting its ability to detect cancer and associated risks of serious adverse effects. More research is needed to clarify the evidence base.

Oct 12, 2016
Journal Article

Influence of Age and Comorbidity on Colorectal Cancer Screening in the Elderly

Screening for colorectal cancer would benefit from re-evaluation of age-based guidelines as well as improved screening completion among the elderly.

Sep 13, 2016
Journal Article

Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

This study systematically reviewed the evidence on the effectiveness, diagnostic accuracy, and harms of colonoscopy, flexible sigmoidoscopy, computed tomographic colonography, and stool tests for colorectal cancer screening.

Jun 27, 2016
Journal Article

Association Between Primary Care Visits and Colorectal Cancer Screening Outcomes in the Era of Population Health Outreach

Patients who visited their primary care provider one or more times were almost twice as likely to be screened for colorectal cancer and about 30 percent more likely receive a follow-up colonoscopy after a positive screening result.

Jun 24, 2016
Journal Article

Estimation of Benefits, Burden, and Harms of Colorectal Cancer Screening Strategies: Modeling Study for the US Preventive Services Task Force

Comparative modeling of colorectal cancer screening methods for previously unscreened adults found that the use of four strategies over different intervals between the ages of 50 and 75 years yielded a comparable balance of benefit and burden.

Jun 21, 2016
Journal Article

Colorectal Cancer Screening and State Health Insurance Mandates

There is no evidence that state-mandated private health insurance coverage affected the rate of colorectal cancer screening for men or women aged 51-64, compared with Medicare-eligible adults.

Apr 25, 2016
Journal Article

Risks Associated with Anesthesia Services During Colonoscopy

Risk of complications within 30 days of a colonoscopy increases with the use of anesthesia services.

Apr 22, 2016
Journal Article

Time to Colonoscopy After Positive Fecal Blood Test in Four U.S. Health Care Systems

To reduce colorectal cancer mortality, positive fecal blood tests must be followed by colonoscopy.

Feb 22, 2016
Journal Article

Validation of Models Used to Inform Colorectal Cancer Screening Guidelines: Accuracy and Implications

We validated 3 colorectal cancer (CRC) microsimulation models against outcomes from the United Kingdom Flexible Sigmoidoscopy Screening (UKFSS) Trial, a randomized controlled trial that examined the effectiveness of one-time flexible sigmoidoscopy screening to reduce CRC mortality.

Jan 26, 2016
Journal Article

Prevalence, Diagnosis, and Management of Diabetes Mellitus Among Older Chinese: Results from the China Health and Retirement Longitudinal Study

This study aims to estimate prevalence of diabetes mellitus (DM), success in diagnosing, and methods of diabetes management in China.

Jan 25, 2016
Journal Article

Variation in Screening Abnormality Rates and Follow-Up of Breast, Cervical and Colorectal Cancer Screening Within the PROSPR Consortium

This study characterizes variation in screening abnormality rates and timely initial follow-up for common cancer screening tests.

Jan 5, 2016
Journal Article

Affordable Care Act Provision Lowered Out-of-Pocket Cost and Increased Colonoscopy Rates Among Men in Medicare

Colorectal cancer screening is one of the few cancer screenings with an A rating from the US Preventive Services Task Force, meaning that the procedure confers a substantial health benefit.

Dec 11, 2015
Journal Article

Is Self-Referral Associated with Higher Quality Care?

This study assesses the extent to which patients self-refer to cancer specialists and whether self-referral is associated with better experiences and quality of care.

Oct 29, 2015
Journal Article

Tumor Board Participation Among Physicians Caring for Patients with Lung or Colorectal Cancer

Multidisciplinary tumor board meetings are common in cancer care, but limited evidence is available about their benefits. We assessed the associations of tumor board participation and structure with care delivery and patient outcomes.

May 29, 2015
Journal Article

Colon Cancer Treatment Often Is Less Aggressive Than Recommended by Research

New results from a major initiative on the quality of cancer care in the U.S. have found that patients with a common type of colon cancer—especially older patients—often are not treated as aggressively with chemotherapy as research shows is necessary to improve survival.

Jan 1, 2010

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Colorectal Cancer