Stepped Care for Depression at Integrated Chronic Care Centers (IC3) in Malawi

Study Protocol for a Stepped-Wedge Cluster Randomized Controlled Trial

Published in: Trials, Volume 22, Article number 630 (2021). doi: 10.1186/s13063-021-05601-1

Posted on on March 29, 2022

by Ryan K. McBain, Owen Mwale, Todd Ruderman, Waste Kayira, Emilia Connolly, Mark Chalamanda, Chiyembekezo Kachimanga, Brown David Khongo, Jesse Wilson, Emily Wroe, et al.

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This study will conduct a stepped-wedge cluster randomized trial to compare the effects of an evidence-based depression care model versus usual care on depression symptom remediation as well as physical health outcomes for chronic care conditions. If determined to be cost-effective, this study will provide a model for integrating depression care into HIV clinics in additional districts of Malawi and other low-resource settings with high HIV prevalence.

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