Research Brief
Examining Possible Causes of Gulf War Illness: RAND Policy Investigations and Reviews of the Scientific Literature
Nov 25, 2005
A Review of the Scientific Literature as it Pertains to Gulf War Illnesses
Volume 8: Pesticides
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This report summarizes the scientific literature on 12 of the 35 pesticides that are likely to have been used during the Persian Gulf War. Where possible, it focuses on known pesticide exposures or doses and related health outcomes that may be relevant to symptoms reported by some Gulf War veterans. Particular attention is paid to long-term, chronic effects of reported exposures to organophosphate and carbamate pesticides. Evidence from epidemiological studies, studies of genetic and biological differences between ill and healthy subjects, and studies of the physiological mechanisms of organophosphate and carbamate pesticides is suggestive, but not conclusive, that these pesticides could be among the potential contributing agents to some of the undiagnosed illnesses seen in Gulf War veterans. However, no prospective studies have been conducted that positively identify pesticides as causative agents. More research is needed to confirm or refute a causal link between pesticides and other agents and the symptoms associated with Gulf War illnesses.
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Table of Contents
Preface PDF
Figures PDF
Tables PDF
Summary PDF
Acknowledgments PDF
Acronyms and Abbreviations PDF
Chapter One
Introduction PDF
Chapter Two
Pesticides PDF
Chapter Three
Health Problems in PGWV PDF
Chapter Four
Lindane PDF
Chapter Five
DEET PDF
Chapter Six
Pyrethroids PDF
Chapter Seven
Organophosphates and Carbamates PDF
Chapter Eight
Confounding Factors: Individual Differences and Interactions PDF
Chapter Nine
Concluding Remarks PDF
Appendix
Comparison by Symptom Category of Subjects with AChE-Inhibitor Exposure (Organophosphate or Carbamate) and Ill PGWV PDF
Bibliography PDF
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This research was sponsored by the RAND National Security Research Division and RAND Health.
This report is part of the RAND Corporation monograph report series. The monograph/report was a product of the RAND Corporation from 1993 to 2003. RAND monograph/reports presented major research findings that addressed the challenges facing the public and private sectors. They included executive summaries, technical documentation, and synthesis pieces.
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