Sleep Disturbances and Nocturnal Symptoms
Relationships with Quality of Life in a Population-Based Sample of Women with Interstitial Cystitis/Bladder Pain Syndrome
Published in: Journal of Clinical Sleep Medicine, v. 10, no. 12, Dec. 2014, p. 1331-1337
Posted on RAND.org on January 07, 2015
- What is the nature and prevalence of sleep disturbances among women with interstitial cystitis/ bladder pain syndrome?
- Do sleep disturbances affect quality of life for women with interstitial cystitis/bladder pain syndrome?
STUDY OBJECTIVES: To characterize the nature and impact of sleep disturbances on quality of life (QOL) in women with interstitial cystitis/ bladder pain syndrome (IC/BPS). METHODS: Participants were 3,397 women from a telephone probability survey who met IC/BPS symptom criteria. Sleep quality, duration, and IC/BPS nocturnal symptoms (i.e., trouble sleeping due to bladder pain, urgency, or needing to use the bathroom), general QOL (mental and physical health and sexual functioning), and IC/BPS QOL impairment were assessed via self-report during telephone interview. RESULTS: Over half of the sample reported poor sleep quality, sleep duration =6 hours, or trouble sleeping due to IC/ BPS symptoms. After covariate adjustment, short sleep duration was significantly associated with greater IC/ BPS QOL impairment (beta = -0.04; p<0.001) and poorer self-reported physical health (beta = 1.86; p < 0.001). Poor sleep quality was significantly associated with greater IC/ BPS QOL impairment (beta = 0.06; p < 0.001), poorer self-reported physical health (beta = -2.86; p < 0.001), and greater sexual dysfunction (beta = -0.04; p < 0.05). IC/ BPS nocturnal symptoms were significantly associated with greater IC/ BPS impairment (beta = 0.14; p < 0.001), poorer physical health (beta = -2.76; p < 0.001) and mental health (beta = 0.52; p < 0.01), and greater sexual dysfunction (beta = -0.10; p < 0.001), after covariate adjustment. After further adjustment for IC/ BPS nocturnal symptoms, we found that poor sleep quality and short sleep duration were independent correlates of poor self-reported physical health. CONCLUSIONS: Poor sleep quality and short sleep duration, as well as disorder-specific sleep disturbances, are highly prevalent in women with IC/ BPS and are associated with poorer disease-specific and general QOL.
- Sleep problems are very prevalent among women with interstitial cystitis/bladder pain syndrome.
- Some sleep disturbances experienced by patients with this condition are general in nature, rather than symptoms of the disorder itself.
Interventions to improve sleep could improve quality of life for this population.