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The Proliferation Security Initiative (PSI) is a cooperative effort to prevent or at least inhibit the spread of weapons of mass destruction (WMD), their delivery systems, and related materials to or from states or non-state actors whose possession of such items would be a serious threat to global or regional security. Currently, 93 countries have endorsed PSI's purpose and principles and participate in its activities. This manual — consisting of nine lecture and seminar sessions that can be used together or alone, in full or in part—is intended for use and adaptation by the U.S. Geographic Combat Commands in training personnel assigned to them for participation in PSI activities. Its purpose is to help the Commands deal with normal issues arising from staff turnover and with any insufficiencies in institutional memory. The sessions cover PSI history and background; PSI design and interdiction principles; U.S. laws relevant to PSI; International agreements relevant to PSI; incentives and disincentives for PSI participation; detection of WMD, their delivery systems, and related materials; PSI exercises and lessons learned; responding to issues challenging PSI; and enhancing capabilities for PSI participation.

The research described in this report was prepared for the Office of the Secretary of Defense (OSD). The research was conducted in the RAND National Defense Research Institute, a federally funded research and development center sponsored by the OSD, the Joint Staff, the Unified Combatant Commands, the Department of the Navy, the Marine Corps, the defense agencies, and the defense Intelligence Community.

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